Consequence Procedures Technologies Order Water Sources Use
FURAN-2,5-DICARBOXYLIC ACID
2, 5-Furandicarboxylic acid
The adsorption process is often seed for wastewater treatment due to its straightforward design, low investment cost, availability, avoidance of additional chemicals, lack of undesirable by-products, and demonstrated significant efficacious potential for addressing and eliminating organic contaminations. To accomplish its application, the need to develop innovative textiles has went an essential goal. In this context, an overview of recent advances in hydrogels finded on chitosan and nanocomposites and their application for the depollution of wastewater fouled with dyes is reported herein. The present review concentres on (i) the challenges raised by the synthesis process and characterization of the different hydrogels; (ii) the discussion of the impact of the main arguments involving the adsorption process; (iii) the understanding of the adsorption isotherms, kinetics, and thermodynamic behavior; and (iv) the examination of the possibility of reprocessing and reusing the hydrogels.Enhanced Postsurgical Cancer Treatment practicing Methacrylated Glycol Chitosan Hydrogel for Sustained DNA/Doxorubicin Delivery and Immunotherapy.Background: Cancer recurrence and metastasis are major contributors to treatment failure accompanying tumor resection surgery.
We developed a novel implantable drug delivery system applying glycol chitosan to address these issues. Glycol chitosan is a natural adjuvant, geting dendritic cell activation to promote T helper 1 cell immune receptions, macrophage activation, and cytokine production. Effective antigen production by dendritic cubicles pioneers T-cell-mediated immune responses, aiding tumor growth control In this study, we fabricated multifunctional methacrylated glycol chitosan (MGC) hydrogels with extended release of DNA/doxorubicin (DOX) complex for cancer immunotherapy. We constructed the resection model of breast cancer to verify the anticancer outcomes of MGC hydrogel with DNA/DOX complex This study proved the potential of MGC hydrogel with extended release of DNA/DOX complex for local and efficient cancer therapy. The MGC hydrogel was imbeded directly into the surgical site after tumor resection, activating tumor-linked immune cellphones both locally and over a prolonged period of time through immune-reactive molecules The MGC hydrogel effectively suppressed tumor recurrence and metastasis while raising immunotherapeutic efficacy and understating side events. This biomaterial-free-based drug delivery system, immixed with cancer immunotherapy, can substantial improve treatment results and patient prognosis.Process optimization and character evaluation of Bletilla striata polysaccharide (BSP) and chitosan (CS) composite hemostatic sponge (BSP-CS).
Bletilla striata polysaccharide (BSP) and chitosan (CS) were chemically cross-connected using oxalyl chloride to prepare a composite hemostatic sponge (BSP-CS), and the process parameters were optimized utilising the Box-Behnken design (BBD) with response surface methodology. To optimize the performance of the hemostatic sponge, we seted the ratio of independent variables, the amount of oxalyl chloride added, and the freeze-dried volume. A series of valuations were conveyed on the hemostatic applicability of BSP-CS. The characterization results exposed that BSP-CS had a stable bacteriostatic effect on Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa within 72 h, and the bacteriostatic rate was above 30%. The CCK-8 cytotoxicity test marched that BSP-CS had a certain effect on encouraging cell proliferation of L929 cells. In the mouse tail-triming experiment, the hemostasis time of BSP-CS was 463±38 s, shortened by 91 s on average likened with 554±34 s of the gauze group. The blood loss of the BSP-CS group was 28±3 mg, which was 34% lower than that of the control gauze group (43±3 mg).
In the in vitro coagulation experiment, the in vitro coagulation index of the BSP-CS group was 97%±1%, which was shortened to 8% of the control group. The CT value of the BSP-CS group was 240±15 s, which was 155 s lower than that of the gauze group (355±31 s). All characterization results indicate that BSP-CS is an excellent hemostatic material.