It Has Been Widely And Deeply Used In The Field Of Medicine
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2, 5-Furandicarboxylic acid
At present, it is mainly used in tissue regeneration and repair, hemostasis and wound healing, antibacterial and anti-infection, disease diagnosis and treatment detection, and drug delivery. In the field of anesthesia, chitosan is considered as a potential perfect carrier for the holded release of amide local anaesthetics. This document aims to analyze the current application of chitosan as a prolonged-release substance in amide-type local anesthetics, encapsulate the related research advances, and subsequently investigate the practicality and candidates of its medical uses.Study on the denitrification and dephosphorization of the aqueous solution by Chitosan/4A Zeolite/Zr established Zeolite.The ternary hybrid material chitosan/4A Zeolite/Zr finded Zeolite was synthesised by expending 4A zeolite molecular sieve, Zr-zeolite and chitosan acetic acid solution as initiating materials. The prepared composite were characterised by SEM, FT-IR and XRD.
The experimental considerations such as the concentration of chitosan acetic acid solution, mass ratio of mass ratio of chitosan acetic acid solution, 4A zeolite molecular sieve and Zr-zeolite functional material, the optimum calcination temperature were optimized. Under this optimum statusses, the denitrification and dephosphorization effect can reach more than 70% when pH value was at 3-9. Dynamics research upshots pointed that the ammonia nitrogen and phosphorus removal progress by chitosan/4A Zeolite/Zr free-based Zeolite was in accordance could be well discovered by the pseudo-second-order kinetic model, and the adsorption rate is up to 6 g/min. The isothermal adsorption process was in accordance with Freundlich model.High-Dose Vitamin D3 and Tonsillectomy as Therapeutic Management in Henoch-Schönlein Purpura tracing Hepatitis B Vaccination: A Rare Case Report.Henoch-Schönlein purpura (HSP) is an immunoglobulin A (IgA)-mediated systemic vasculitis, which is one of the rare adverse responses to hepatitis B vaccination. Low vitamin D degrees were chanced to be present in the majority of HSP patients.
A 19-year-old woman was allowed with a purpuric rash on bilateral lower limbs and joint pain on her left index finger in January 2020. A previous history of rash comed one week after the patient obtained her first dose of recombinant hepatitis-B vaccination. Routine hematological examination, creatinine, urinalysis, C3, and C4 recorded normal results Anti-HCV, and ANA tests were negative, and anti-HBs were upgraded. Vitamin D is very low. The patient was named with HSP and holded mycophenolate mofetil, methylprednisolone, vitamin D3, and folic acid. Within 1 month of therapy, the rash still occurred frequently, so mycophenolate mofetil was varyed to mycophenolic acid, the dose of methylprednisolone was increased and fexofenadine was distributed. In the next 3 months, the rash has bettered patients accounted knee joint pain and hair loss.
In May 2021, the patient underwent tonsillectomy due to acute exacerbation of chronic tonsillitis the patient described that the rash had completely concluded and never worsened, and the vitamin D assay was normal.Hepatitis B vaccination is one of the aetiologys of HSP, although it is rare, so it is important to ask about the vaccination history in patients with mistrusted HSP. Correction of vitamin D and performing tonsillectomy provide better treatment results in HSP founts in this patient.Notoginsenoside R1 Ameliorate High-Fat-Diet and Vitamin D3-Induced Atherosclerosis via Alleviating Inflammatory Response, Inhibiting Endothelial Dysfunction, and governing Gut Microbiota.AIM: Natural medicaments possess significant research and application value in the field of atherosclerosis (AS) treatment. The study was performed to investigate the encroachments of a natural drug component, notoginsenoside R1, on the development of atherosclerosis (AS) and the potential mechanisms Rats geted with AS by a high-fat-diet and vitamin D3 were processed with notoginsenoside R1 for six hebdomads. The ameliorative effect of NR1 on AS rats was measured by observing pathological alterations in the abdominal aorta, biochemical powers in serum and protein expression in the abdominal aorta, as well as by psychoanalysing the gut microbiota The NR1 group exhibited a noticeable reduction in plaque pathology.